Nintendo DS On Your Mac Or PC
DeSmuME is a Nintendo DS emulator for the Mac and for the PC that gives you the full functionality of the DS; buttons, touchscreen interface and even the Wi-Fi connectivity. It’s feature packed and allows you to play both Homebrew games and ROM images. It also offers some extra features that are not available on a physical DS like taking screenshots, creating movies from game play, loading cheat codes and even saving your game play.
It’s 100% free and can be downloaded from here. You might also want to check out NDS Homebrew for an impressive collection of homebrew games and applications.
Seemed pretty nice but ran slow on my PC. Going to give it another try on my Macs.
I found that it runs faster on the Mac myself. It's not perfect, but it's a start.
I have a mac 10.4.11 and i can't find a good emulator for the DS. DeSmuME doesn't work on the 10.4 i guess.